Gamma Oscillation - Induced Plasticity in Area CA 3 of the hippocampus

...................................................................................... ...............5 Abstract in German ..........................................................................................7in German ..........................................................................................7 Introduction ...................................................................................................9 1. Anatomy and connectivity of the hippocampus........................................................9 2. Intrahippocampal connections ...........................................................................9 3. Extrahippocampal connections .........................................................................10 3.1. Input ......................................................................................................10 3.2. Output ....................................................................................................11 4. Hippocampal cells ........................................................................................14 4.1. Principal cells ........................................................................................14 4.2. Diversity of hippocampal interneurons ............................................................15 4.2.1. Perisomatic-targeting interneurons .............................................................16 4.2.1.1. Basket cells ......................................................................................16 4.2.1.2. Axo-axonic cells ................................................................................16 4.2.2. Dendritic inhibitory interneurons ................................................................17 4.2.2.1. Bistratified cells .................................................................................17 4.2.2.2. Trilaminar cells. .................................................................................17 4.2.2.3. Oriens-lacunosum moleculare cells ..............................................................18 5. Network oscillatory activity in the Hippocampus ....................................................18 5.1. Gamma oscillations in vivo and in vitro ..........................................................18 5.1.1. Firing patterns in gamma frequency oscillations. ...........................................19 5.1.1.1. Principal cells. .................................................................................20 5.1.1.2. Interneurons ..................................................................................20 5.2. Theta Oscillations. ...................................................................................22 5.2.1. Pyramidal cells .................................................................................23